Smart Basics Catalog--Pyruvate

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CALVATE Calcium Pyruvate (Pyruvic Acid)
Pyruvate, a natural by-product of metabolism, is also found in certain foods, primarily fruits and vegetables. In the human body pyruvate is generated when glucose (a six-carbon molecule) yields two molecules of pyruvate (a three-carbon molecule), or more specifically, pyruvic acid. Two potential mechanisms by which pyruvate enhances both fat and weight loss are through increasing metabolism and fat utilization. Although animal studies have shown that pyruvate increases resting metabolic rate and fat utilization (as determined by a decrease in respiratory quotient), increased metabolic rate hasn't been found in humans. Still, preliminary data indicate that pyruvate may increase fat utilization in humans. Now, after 25 years of research, pyruvate is available as a dietary supplement with some unique properties. Recent clinical studies have found that pyruvate produces a remarkable physiological and metabolic change in those who take it. Some of these remarkable results from the use of this product are: Increased anabolism or body protein uptake. Decreased body fat. Retention of lean muscle mass. Increased glycogen storage. Increased muscular endurance. Train and compete at high intensity and strength with Pyruvate. Pyruvate for Weight Loss Pyruvate has been shown to increase weight loss by up to 37% in clinical studies, reduce fat without exercise, and is predicted to be a more potent fat burner than HCA and chromium picolinate together. Two well-controlled human studies were conducted at the Clinical Research Center at the University of Pittsburgh School of Medicine. The results we phenomenal. They found that pyruvate had a "significant impact not only on weight loss, but more important, on fat loss." The most recent study found that when obese female subjects were given pyruvate for three weeks, they lost 37% more weight (13 vs. 9.5 pounds) and 48% more fat (8.8 vs. 5.9 pounds). This means an extra pound of body fat every week!! Pyruvate for Endurance According to human studies, pyruvate improves exercise performance primarily by enhancing the transport of glucose into the muscle cell in a process known as glucose extraction. Dr Ronald Stanko, MD: "No matter what the exercise, people are able to do more longer, yet without the unwanted side effects that one would get with caffeine or some other stimulant." Pyruvate will give you "natural energy" without artificial stimulants. Clinical tests have shown increased muscular endurance in both the arms and legs by 20%. Olympic gold-medal gymnast Shannon Miller used pyruvate to help energize her before the 1996 Olympics. Pyruvate has been shown to increase the resting metabolic rate and fat utilization. What about side effects? (this is the good part) Dr. Frank Greenway says that Pyruvate is, "a normal constituent of human metabolism, so it's safety should be high." Even in VERY high doses (100 x the currently recommended dose), "No changes were seen in standard laboratory testing or clinical evaluations that included measurements of heart rate, blood pressure, body temperature, EKG, and urine output." Dr. Stanko sums up 25 years of research into pyruvate by saying, "I'm convinced that pyruvate is not only effective but also has no serious side effects." Why Calcium Pyruvate? Besides causing intestinal distress and upset, pyruvic acid is chemically unstable and must be stabilized in the form of a salt. This is accomplished by chemically combining pyruvic acid with with either magnesium, potassium, arginine, sodium or calcium. While all these can be used to stabilize pyruvic acid into a pyruvate supplement, they're not all "created equal" as we will show you. According to Dr. Carl Coppolino, there are disadvantages to creating forms of pyruvate other than calcium pyruvate. Remember, each molecule of pyruvate must contain a certain percentage of a stabilizing counterpart. Let's see how that works out with other pyruvate combinations: Magnesium pyruvate: excessive magnesium supplementation can cause digestive disturbances--diarrhea in particular and may increase the risk of hip fractures. Potassium pyruvate: excess supplementation of potassium is dangerous for the elderly and for patients suffering from renal impairment. Also at risk are those taking certain prescription drugs. Arginine pyruvate: In large doses, arginine can cause bone disorders, and can produce nausea and vomiting. Sodium pyruvate: excess intake of sodium has been associated with the development of hypertension, and considered the major culprit in causing many of the health problems of modern civilization such as strokes and other cardiovascular diseases. Sodium pyruvate products often contain diuretics in an attempt to counteract the sodium. Calcium Pyruvates' Advantage According to Art Ulene, M.D., calcium plays a role in bone and tooth formation, blood clotting, heart rhythm, nerve transmission, muscle growth and contraction, and the proper functioning of cell membranes. In addition, calcium contributes to lower blood pressure and may protect against colon cancer. In fact, the most common problem related to long-term calcium deficiency is osteoporosis, a condition in which bones lose their normal density and strength. With the RDA for calcium being 800 - 1000 mgs., calcium pyruvate is one more effective source. Calvate (Calcium-Pyruvate), from ASN. Each capsule provides: Pyruvic Acid . . . . . . .500 mg Calcium . . . . . . . . . . 110 mg L-Glycine . . . . . . . . .250 mg B2 (Riboflavin) . . . . . 1.6 mg B3 (Niacinamide) . . . . 2.3 mg Bioperine® . . . . . . . . 1.5 mg Suggested Use: Two (2) to four (4) capsules, 1 to 3 times a day on an empty stomach, with water, or as directed by a health practitioner.

CALVATE
Calcium Pyruvate (Pyruvic Acid)

Pyruvate, a natural by-product of metabolism, is also found in certain foods, primarily fruits and vegetables. In the human body pyruvate is generated when glucose (a six-carbon molecule) yields two molecules of pyruvate (a three-carbon molecule), or more specifically, pyruvic acid. Two potential mechanisms by which pyruvate enhances both fat and weight loss are through increasing metabolism and fat utilization. Although animal studies have shown that pyruvate increases resting metabolic rate and fat utilization (as determined by a decrease in respiratory quotient), increased metabolic rate hasn't been found in humans. Still, preliminary data indicate that pyruvate may increase fat utilization in humans. Now, after 25 years of research, pyruvate is available as a dietary supplement with some unique properties. Recent clinical studies have found that pyruvate produces a remarkable physiological and metabolic change in those who take it. Some of these remarkable results from the use of this product are:

Increased anabolism or body protein uptake.

Decreased body fat.

Retention of lean muscle mass.

Increased glycogen storage.

Increased muscular endurance.

Train and compete at high intensity and strength with Pyruvate.

Pyruvate for Weight Loss
Pyruvate has been shown to increase weight loss by up to 37% in clinical studies, reduce fat without exercise, and is predicted to be a more potent fat burner than HCA and chromium picolinate together. Two well-controlled human studies were conducted at the Clinical Research Center at the University of Pittsburgh School of Medicine. The results we phenomenal. They found that pyruvate had a "significant impact not only on weight loss, but more important, on fat loss." The most recent study found that when obese female subjects were given pyruvate for three weeks, they lost 37% more weight (13 vs. 9.5 pounds) and 48% more fat (8.8 vs. 5.9 pounds). This means an extra pound of body fat every week!!

Pyruvate for Endurance
According to human studies, pyruvate improves exercise performance primarily by enhancing the transport of glucose into the muscle cell in a process known as glucose extraction. Dr Ronald Stanko, MD: "No matter what the exercise, people are able to do more longer, yet without the unwanted side effects that one would get with caffeine or some other stimulant."

Pyruvate will give you "natural energy" without artificial stimulants. Clinical tests have shown increased muscular endurance in both the arms and legs by 20%. Olympic gold-medal gymnast Shannon Miller used pyruvate to help energize her before the 1996 Olympics. Pyruvate has been shown to increase the resting metabolic rate and fat utilization.

What about side effects? (this is the good part)
Dr. Frank Greenway says that Pyruvate is, "a normal constituent of human metabolism, so it's safety should be high." Even in VERY high doses (100 x the currently recommended dose), "No changes were seen in standard laboratory testing or clinical evaluations that included measurements of heart rate, blood pressure, body temperature, EKG, and urine output."

Dr. Stanko sums up 25 years of research into pyruvate by saying, "I'm convinced that pyruvate is not only effective but also has no serious side effects."

Why Calcium Pyruvate?
Besides causing intestinal distress and upset, pyruvic acid is chemically unstable and must be stabilized in the form of a salt. This is accomplished by chemically combining pyruvic acid with with either magnesium, potassium, arginine, sodium or calcium. While all these can be used to stabilize pyruvic acid into a pyruvate supplement, they're not all "created equal" as we will show you.

According to Dr. Carl Coppolino, there are disadvantages to creating forms of pyruvate other than calcium pyruvate. Remember, each molecule of pyruvate must contain a certain percentage of a stabilizing counterpart. Let's see how that works out with other pyruvate combinations:

Magnesium pyruvate: excessive magnesium supplementation can cause digestive disturbances--diarrhea in particular and may increase the risk of hip fractures.

Potassium pyruvate: excess supplementation of potassium is dangerous for the elderly and for patients suffering from renal impairment. Also at risk are those taking certain prescription drugs.

Arginine pyruvate: In large doses, arginine can cause bone disorders, and can produce nausea and vomiting.

Sodium pyruvate: excess intake of sodium has been associated with the development of hypertension, and considered the major culprit in causing many of the health problems of modern civilization such as strokes and other cardiovascular diseases. Sodium pyruvate products often contain diuretics in an attempt to counteract the sodium.

Calcium Pyruvates' Advantage
According to Art Ulene, M.D., calcium plays a role in bone and tooth formation, blood clotting, heart rhythm, nerve transmission, muscle growth and contraction, and the proper functioning of cell membranes. In addition, calcium contributes to lower blood pressure and may protect against colon cancer. In fact, the most common problem related to long-term calcium deficiency is osteoporosis, a condition in which bones lose their normal density and strength. With the RDA for calcium being 800 - 1000 mgs., calcium pyruvate is one more effective source.

Calvate (Calcium-Pyruvate), from ASN. Each capsule provides:

Pyruvic Acid . . . . . . .500 mg
Calcium . . . . . . . . . . 110 mg
L-Glycine . . . . . . . . .250 mg
B2 (Riboflavin) . . . . . 1.6 mg
B3 (Niacinamide) . . . . 2.3 mg
Bioperine® . . . . . . . . 1.5 mg

Suggested Use: Two (2) to four (4) capsules, 1 to 3 times a day on an empty stomach, with water, or as directed by a health practitioner.

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